I found that taking doses at night to be helpful in the first few weeks. After that, I seemed to get used to the medication (this was Prozac and Effexor, at different times) after that and didn't feel as drowsy. Now I'm taking Elavil for chronic pain, so I take it at night and the low dose of Effexor in the daytime and I'm not having problems with drowiness. I also drink tea constantly throughout the day, so maybe that offsets some drowsiness?

Better living through chemicals, as one of my doctors used to say.